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What kinds of cancer can OncoK9 detect?

OncoK9 is a multi-cancer early detection test meaning it detects multiple classes of genomic alterations associated with a wide variety of cancers. You can view a list here of the 30 different cancers that OncoK9 detected in at least one affected patient in the clinical validation study. View this information at the PetDx Veterinary Support website.
 

How early can OncoK9 detect cancer?

OncoK9 has been designed to detect cancer-associated genomic alterations that are present even in very early-stage cancers. As a result, OncoK9 may detect cancer early, while it is still localized to the primary site and can be treated with curative intent. A positive test result indicates the presence of malignant tumor in the body. The fraction of cancer cases detectable by the test increases with cancer stage. When used for Screening in patients without clinical signs suggestive of cancer, repeat testing at annual intervals will increase the likelihood of detecting cancer by OncoK9.
 

What do I do after a positive OncoK9 test?

Each case is different, and follow-up diagnostic workup is at the discretion of the veterinarian. A cancer-focused clinical evaluation is advised, with a thorough physical exam (including oral and rectal exam), thoracic and abdominal imaging, and sampling of any masses or enlarged lymph nodes found on exam or workup. Advanced imaging such as CT, MRI, or PET or other diagnostics may also be indicated.

Vaccinology 
Some of the biggest controversies surrounding veterinary medicine is the judicious use of
vaccines. When to give, how often to give; who needs what, and ultimately, should vaccines
even be given to certain individuals. The COVID pandemic likely stirred discussion about the
current proper usage of vaccines.
I think that there is a large population of veterinarians that recommend boosters of the core

vaccines (Distemper, Parvovirus, and Rabies) every year. And, I think that that is a greed-
generated thought process. Multiple year vaccines have been available since the early 1980's.

Interestingly, a study was released recently looking at vaccine antibody titers in a colony of cats.
These cats were in a colony for minor research and were vaccinated as kittens. Since they were
in a “closed” environment their entire lives, the vaccines given as kittens were never boostered,
meaning these cats had one set of shots at the start of their lives and never received any
vaccines thereafter. Antibody titers were done periodically throughout their lives finding that their
antibody levels remained “good” throughout their entire lives.
So what does that say to those veterinarians that boost vaccines yearly in indoor cats?
Completely unnecessary.
Core vaccines continue to be Canine and Feline Distemper, Rabies, Parvovirus in dogs, Feline
Leukemia in cats. In our environment, we vaccinate against Leptospirosis due to the potential
for infection. Canine Influenza and Kennel Cough vaccines are available to those dogs at high
risk of infection (boarding kennels, grooming salons, agility competitors, etc.).
In our practice, to vaccinate or not is determined by your pet's lifestyle (indoor/outdoor cats,
potential exposure to Leptospirosis via wildlife, and your pet's age). I stop all vaccines when
your pet is 13 – 14 years of age with the exception of kennel cough vaccines prior to boarding
them in a kennel. We will also not vaccinate your pet if we think the vaccine poses a higher risk
for adverse effects than the natural exposure to disease. For example, if your pet has an
ongoing health issue, vaccinating him/her may actually be contraindicated. We pick and choose
our use of vaccines.
An alternative to vaccine use is measuring antibody levels every 2-4 years. If the antibody level
dips below what is considered safe, then a booster is warranted. We have been astounded as to
how long some individuals maintain high levels of antibodies over the years.

ALLERGIES IN DOGS

Does your pet scratch? Does your lick his or her feet? Does your pet scratch at their ears?
Allergies are very common in our pets; they can be allergic to environmental allergens, food,
and fleas, amongst other things. Your pet might only scratch at one ear and that might be the
only symptom that they manifest.
Allergies begin, generally, but not always, as early as 1-2 years of age. The symptoms might be
seasonal or year-round depending on the offending allergen.
When you and I suffer from allergies, our offending allergens are often inhaled, and the
“reaction” or symptom is generally sneezing, runny eyes, coughing, etc. However, in the dog,
the offending allergen is absorbed through the skin and the “reaction” is generally cutaneous,
but can result in coughing, sneezing, and runny eyes as well. As mentioned above, some dogs
only have ear inflammation (infection, hypersecretion of wax or cerumen, ear flap inflammation)
or they may lick their feet. But, by and large, constant scratching is the most common clinical
complaint. Trauma to the skin, via scratching (pruritus), can and does lead to secondary skin
infection.
So what do we do about allergies (discussion confined to environmental allergies). Historically,
veterinarians only had a few medications in the cabinet – antihistamines and steroids. Luckily
those days are gone and I do mean luckily. Steroids were very effective but the side effects,
both short and long-term were terrible.
Now we are blessed to have two new drugs in our cabinets: Apoquel and Cytopoint. Both of
these medications are targeted therapies. Apoquel inhibits a single enzyme in the skin that
stops the cascade of biochemical and molecular events that start the allergy process. Apoquel
is given orally, daily, and is very effective in most cases with very few observed side effects
Cytopoint is an injection given monthly to every six weeks; Cytopoint is a monoclonal antibody
that neutralizes the inflammatory proteins (cytokines) that, again, initiate the allergy cascade. It
is also very effective with no real side effects.
Lastly, we have allergy testing and immunotherapy. We can draw blood from your pet and
determine what your pet is allergic to and then create a “kit” of those allergens; the
immunotherapy is available as an injection but currently we recommend the sublingual drops.
The sublingual drops have reported to be more effective and “work” more rapidly than the
injection system. And, we can avoid giving injections to our pets.
We, thankfully, have come a long way in improving our pet's lives and reshaping how we
approach the scratchy and itchy dog.
We have come a very long way in improving the lives of our pets, including the chronic
scratching, licking, head-shaking pet. And, the medications are now very effective and have few
side effects.
If you feel your pet has allergies, call us for a consultation/examination

Yellow Flowers

TO NEUTER/SPAY OR NOT TO NEUTER/SPAY

For the past 60-70 years it has generally been recommended to spay and neuter cats and dogs.
Initially, some of this “idea” stemmed from preventing over population of dogs and cats. It was
then found that spaying or neutering your pet decreases the risk of certain diseases (mammary
cancers, infection of the uterus). In neutering male cats, it decreased the risk of behavioral
issues, urine spraying, etc. Neutering a male dog also diminished behavioral issues, certain
sexually transmissible diseases. However, some of these ideas are changing
It goes without saying that spaying your female dog decreases or, in some instances, eliminates
the risk of mammary cancers. A study showed that the risk of breast cancer was 0.05% in dog
and cats less than 6 months of age. Spaying a cat or dog at 18 months or older, the risk rose to
100%.
However, recent studies have looked at “delaying” the procedure and the impact that has on
reducing other cancers, decreasing the risk of obesity, Diabetes, urinary incontinence and a
myriad of other diseases. Delaying spaying a female or neutering a male dog dramatically
reduces the risk of lifetime obesity. By reducing the pet's weight, this is likely responsible for
diminishing the risk of osteoarthritis, cruciate ligament tears, etc.


So our recommendation is as follows:
• Cats: we recommend spaying or neutering your kitty at 6 months or slightly younger.
Neutering a male cat prior to puberty reduces or eliminates spraying and prevents, in the
female, constant heat cycles (female cats will stay in heat, more or less, until
impregnated).
• Dogs: we recommend delaying the spaying/neutering of dogs until they are, at least, 1
year of age. We recommend delaying spaying/neutering giant breeds until 2 year of age.

Closeup of a Black Dog

Solensia

Cats hide almost everything, especially pain. But if your cat is dealing with osteoarthritis (OA) pain, you’ve probably noticed changes in their everyday behavior. Things like jumping, climbing stairs, and even playing might not be so easy for them.

Available later in 2022, Solensia is a monthly injection administered at your vet's office that can help control the pain your cat may experience from OA.

What Is Cat OA Pain?

OA is a type of arthritis that occurs when the tissue in your cat’s joints starts to get worn down, causing bones to rub against one another. You’d think this just makes moving harder, but OA can also cause severe pain. Without treatment, your cat's pain can continue to get worse.

Why Solensia?

While cat OA isn’t curable, the pain from OA can now be effectively managed.

Solensia helps your cat get back to moving more freely again and stops OA pain from disrupting the unique bond they share with you.

What to Expect With Solensia

In a clinical study, cat owners reported that Solensia improved their cat’s quality of life, comfort, and overall well-being.

  • Controls OA pain in cats, which can lead to an easier time moving.

  • A once-monthly injection given at your vet's office

  • Works like your cat's naturally made antibodies to reduce pain signals.

Neva Masquerade Cat

INTERNAL MEDICINE

Dr. Dorsam has been in practice for nearly forty-five years. In those many years, he has
developed a very special interest in internal medicine. Solving involved medical cases has been
and continues to be a great passion for him. And, because our practice is located two hours
from the nearest specialty practice, that passion and interest is vital to the patients of this
practice.
The clinic has a full in-house laboratory for blood work and we utilize two outside referral
laboratories for more involved testing including PCR testing for identification of blood and
intestinal parasites.
Our most recent addition to the practice is cancer screening via cell-free genomic testing
(OncoK-9) - see “Early Detection Screening for Cancer” on our website's front page. This
unique blood testing can detect thirty different kinds of cancer by detecting the DNA presence of
abnormal cells. This screening is vital to those breeds that are highly predisposed to cancer.
In addition, we have radiologists on call to help support interpretation of radiographs when we
have questions concerning our own interpretation. We are equipped with ultrasound capabilities
as well.
Our pathologist is in the Scottsdale AZ area and we rely upon him for all of our biopsies and
identification of masses and tumors.

Veterinarian with Dog
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